Calcium/Calmodulin-dependent protein kinase
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | <StructureSection load='2vz6' size='450' side='right' scene= caption='Human CamKII subunit α kinase domain complex with indirubin (PDB code [[2vz6]])'> | |
| - | <StructureSection load='2vz6' size='450' side='right' scene= caption=' | + | |
__TOC__ | __TOC__ | ||
== Function == | == Function == | ||
| Line 14: | Line 13: | ||
== Structural highlights == | == Structural highlights == | ||
| - | CAMKII contains an N-terminal catalytic domain which binds ATP and substrate protein, regulatory domain (CBD) and association domain (ASD). DAPK contains a regulatory (RD) and autoinhibitory (AD) domains. | + | CAMKII contains an N-terminal catalytic domain which binds ATP and substrate protein, regulatory domain (CBD) and association domain (ASD). DAPK contains a regulatory (RD) and autoinhibitory (AD) domains. The activity of human CamKII is regulated by autophosphorylation of Thr 286 and Thr 305. |
</StructureSection> | </StructureSection> | ||
Revision as of 12:11, 15 November 2015
| |||||||||||
3D Structures of Ca2+/Calmodulin dependent protein kinase
Updated on 15-November-2015
See also
Calcium-dependent protein kinase, a member of the CaM kinase family
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Alice Harmon, Jaime Prilusky
