CAMP-dependent protein kinase
From Proteopedia
(Difference between revisions)
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In the absence of cAMP, PKA is an inactive tetramer with 2 catalytic subunits and 2 regulatory subunits. The regulatory subunit contains inhibitory region, two cAMP-binding domains and a C-terminal dimerization domain. The catalytic subunit contains an ATP-binding domain and a regulatory subunit binding domain. | In the absence of cAMP, PKA is an inactive tetramer with 2 catalytic subunits and 2 regulatory subunits. The regulatory subunit contains inhibitory region, two cAMP-binding domains and a C-terminal dimerization domain. The catalytic subunit contains an ATP-binding domain and a regulatory subunit binding domain. | ||
| - | *<scene name='46/468128/Cv/3'>cAMP-binding site of catalytic subunit</scene> ([[4ntt]]). | + | *<scene name='46/468128/Cv/3'>cAMP-binding site of catalytic subunit</scene> ([[4ntt]]).<ref>PMID:25077557</ref> |
</StructureSection> | </StructureSection> | ||
==3D structures of cAMP-dependent protein kinase== | ==3D structures of cAMP-dependent protein kinase== | ||
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**[[3j4q]], [[3j4r]] – mPKA + A-kinase anchor protein 18<br /> | **[[3j4q]], [[3j4r]] – mPKA + A-kinase anchor protein 18<br /> | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:12, 19 November 2015
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3D structures of cAMP-dependent protein kinase
Updated on 19-November-2015
References
- ↑ Bastidas AC, Wu J, Taylor SS. Molecular Features of Product Release for the PKA Catalytic Cycle. Biochemistry. 2014 Aug 8. PMID:25077557 doi:http://dx.doi.org/10.1021/bi500684c
