Casein kinase
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
| - | CK2 is a tetramer with a pair of 2 subunits – the α subunit is the catalytic one and the β subunit is the regulatory one. <scene name='46/468136/Cv/2'>CK1 inhibitors bind in the ATP binding pocket</scene>. | + | CK2 is a tetramer with a pair of 2 subunits – the α subunit is the catalytic one and the β subunit is the regulatory one. <scene name='46/468136/Cv/2'>CK1 inhibitors bind in the ATP binding pocket</scene>.<ref>PMID:22877629</ref> |
</StructureSection> | </StructureSection> | ||
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**[[1ds5]] - mCK2 α subunit + β subunit peptide | **[[1ds5]] - mCK2 α subunit + β subunit peptide | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:18, 22 November 2015
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3D Structures of casein kinase
Updated on 22-November-2015
References
- ↑ Hua Z, Huang X, Bregman H, Chakka N, DiMauro EF, Doherty EM, Goldstein J, Gunaydin H, Huang H, Mercede S, Newcomb J, Patel VF, Turci SM, Yan J, Wilson C, Martin MW. 2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1gamma) inhibitors. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5392-5. doi: 10.1016/j.bmcl.2012.07.046. , Epub 2012 Jul 20. PMID:22877629 doi:10.1016/j.bmcl.2012.07.046
