Casein kinase
From Proteopedia
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== Function == | == Function == | ||
| - | '''Casein kinase''' (CK) is a protein kinase which functions as regulator of signal transduction.<br /> | + | '''Casein kinase''' (CK) is a protein kinase which functions as regulator of signal transduction.<ref>PMID:11475410</ref><br /> |
| - | * '''CK1''' is a serine/threonine kinase with several members: α, β1, γ1, γ2, γ3, δ and ε. <br /> | + | * '''CK1''' is a serine/threonine kinase with several members: α, β1, γ1, γ2, γ3, δ and ε.<ref>PMID:9552408</ref> <br /> |
* '''CK2''' functions in cell cycle control, DNA repair and circadian rhythm regulation. | * '''CK2''' functions in cell cycle control, DNA repair and circadian rhythm regulation. | ||
Revision as of 09:20, 22 November 2015
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3D Structures of casein kinase
Updated on 22-November-2015
References
- ↑ Eide EJ, Virshup DM. Casein kinase I: another cog in the circadian clockworks. Chronobiol Int. 2001 May;18(3):389-98. PMID:11475410
- ↑ Pinna LA, Meggio F. Protein kinase CK2 ("casein kinase-2") and its implication in cell division and proliferation. Prog Cell Cycle Res. 1997;3:77-97. PMID:9552408
- ↑ Hua Z, Huang X, Bregman H, Chakka N, DiMauro EF, Doherty EM, Goldstein J, Gunaydin H, Huang H, Mercede S, Newcomb J, Patel VF, Turci SM, Yan J, Wilson C, Martin MW. 2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1gamma) inhibitors. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5392-5. doi: 10.1016/j.bmcl.2012.07.046. , Epub 2012 Jul 20. PMID:22877629 doi:10.1016/j.bmcl.2012.07.046
