CCA-adding enzyme
From Proteopedia
(Difference between revisions)
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'''CCA-adding enzyme''' (CAE) builds or repairs the trinucleotice CCA at the 3’ end of tRNA. CAE has one active site which is capable of binding CTP and ATP in a specific sequence. In the bacteria Aquifex aeolicus, CAE consists of 2 subunits. One specific for CTP and the other for ATP. CAE builds the CCA without a genetic template. | '''CCA-adding enzyme''' (CAE) builds or repairs the trinucleotice CCA at the 3’ end of tRNA. CAE has one active site which is capable of binding CTP and ATP in a specific sequence. In the bacteria Aquifex aeolicus, CAE consists of 2 subunits. One specific for CTP and the other for ATP. CAE builds the CCA without a genetic template. | ||
| - | <scene name='55/551188/Cv/2'>Structure of CCA-adding enzyme complex with tRNA 34-mer, CTP, ethanediol and Ca+2 ion</scene>. | + | *<scene name='55/551188/Cv/2'>Structure of CCA-adding enzyme complex with tRNA 34-mer, CTP, ethanediol and Ca+2 ion</scene> (PDB entry [[3ovs]]). |
| + | *<scene name='55/551188/Cv/3'>Binding site of CCA-adding enzyme</scene> (PDB entry [[3ovs]]).<ref>PMID:21071662</ref> | ||
</StructureSection> | </StructureSection> | ||
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**[[3ovb]] – AfCAE + ATP + tRNA 35-mer<BR /> | **[[3ovb]] – AfCAE + ATP + tRNA 35-mer<BR /> | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:41, 23 November 2015
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3D structures of CCA-adding enzyme
Updated on 23-November-2015
References
- ↑ Pan B, Xiong Y, Steitz TA. How the CCA-adding enzyme selects adenine over cytosine at position 76 of tRNA. Science. 2010 Nov 12;330(6006):937-40. PMID:21071662 doi:10.1126/science.1194985
