CD47

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 12: Line 12:
CD47 consists of an extracellular N-terminal immunoglobulin-like domain, a transmembrane domain and a C-terminal intracellular domain.
CD47 consists of an extracellular N-terminal immunoglobulin-like domain, a transmembrane domain and a C-terminal intracellular domain.
-
*<scene name='53/538855/Cv/2'>CD47 with SIRP α (cyan) and I-ions</scene> ([[2jjs]]).
+
*<scene name='53/538855/Cv/2'>CD47 with SIRP α (cyan) and I-ions</scene> ([[2jjs]]).<ref>PMID:18657508</ref>
</StructureSection>
</StructureSection>
== 3D Structures of CD47 ==
== 3D Structures of CD47 ==
Line 21: Line 21:
[[2vsc]] – hCD47 extracellular domain (mutant) <br />
[[2vsc]] – hCD47 extracellular domain (mutant) <br />
[[4cmm]] - hCD47 extracellular domain (mutant) + tyrosine-protein phosphatase non-receptor type substrate<br />
[[4cmm]] - hCD47 extracellular domain (mutant) + tyrosine-protein phosphatase non-receptor type substrate<br />
-
 
+
== References ==
 +
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 13:25, 24 November 2015

Glycosylated human CD47 residues 19-136 (mutant) (green) complex with SIRP α (cyan) and I- ions 2jjs

Drag the structure with the mouse to rotate

3D Structures of CD47

Updated on 24-November-2015

2jjs, 2jjt, 4kjy – hCD47 extracellular domain (mutant) + SIRP α
2vsc – hCD47 extracellular domain (mutant)
4cmm - hCD47 extracellular domain (mutant) + tyrosine-protein phosphatase non-receptor type substrate

References

  1. Hatherley D, Graham SC, Turner J, Harlos K, Stuart DI, Barclay AN. Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47. Mol Cell. 2008 Jul 25;31(2):266-77. PMID:18657508 doi:10.1016/j.molcel.2008.05.026

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Personal tools