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5dw7

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'''Unreleased structure'''
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==Crystal structure of the unliganded geosmin synthase N-terminal domain from Streptomyces coelicolor==
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<StructureSection load='5dw7' size='340' side='right' caption='[[5dw7]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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The entry 5dw7 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5dw7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DW7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DW7 FirstGlance]. <br>
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Authors: Lombardi, P.M., Christianson, D.W.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dz2|5dz2]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dw7 OCA], [http://pdbe.org/5dw7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dw7 RCSB], [http://www.ebi.ac.uk/pdbsum/5dw7 PDBsum]</span></td></tr>
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Description:
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Lombardi, P.M]]
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[[http://www.uniprot.org/uniprot/CYC2_STRCO CYC2_STRCO]] Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species.<ref>PMID:12556563</ref> <ref>PMID:12563033</ref> <ref>PMID:14995166</ref> <ref>PMID:16787064</ref>
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[[Category: Christianson, D.W]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Cane, D E]]
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[[Category: Chou, W K]]
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[[Category: Christianson, D W]]
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[[Category: Cole, K E]]
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[[Category: Harris, G G]]
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[[Category: Koksal, M]]
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[[Category: Lombardi, P M]]
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[[Category: Matsui, T]]
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[[Category: Murphy, F V]]
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[[Category: Pemberton, T A]]
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[[Category: Vedula, L S]]
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[[Category: Weiss, T M]]
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[[Category: Lyase]]
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[[Category: Terpene cyclase]]

Revision as of 04:45, 1 December 2015

Crystal structure of the unliganded geosmin synthase N-terminal domain from Streptomyces coelicolor

5dw7, resolution 3.20Å

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