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4x2q
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| - | ''' | + | ==Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2== |
| - | + | <StructureSection load='4x2q' size='340' side='right' caption='[[4x2q]], [[Resolution|resolution]] 2.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x2q]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X2Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Retinal_dehydrogenase Retinal dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.36 1.2.1.36] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2q OCA], [http://pdbe.org/4x2q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x2q RCSB], [http://www.ebi.ac.uk/pdbsum/4x2q PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/AL1A2_HUMAN AL1A2_HUMAN]] Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Retinal dehydrogenase]] | ||
| + | [[Category: Amory, J K]] | ||
| + | [[Category: Goldstein, A S]] | ||
[[Category: Paik, J]] | [[Category: Paik, J]] | ||
| - | [[Category: | + | [[Category: Stenkamp, R E]] |
| - | [[Category: | + | [[Category: Trong, I Le]] |
| - | [[Category: | + | [[Category: Dehydrogenase]] |
| + | [[Category: Isozyme]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Spermatogenesis]] | ||
| + | [[Category: Testis]] | ||
Revision as of 16:15, 2 December 2015
Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2
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