5d7n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
==Crystal structure of human Sirt3 at an improved resolution==
-
 
+
<StructureSection load='5d7n' size='340' side='right' caption='[[5d7n]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
-
The entry 5d7n is ON HOLD until Paper Publication
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5d7n]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D7N FirstGlance]. <br>
-
Authors: Rumpf, T., Gerhardt, S., Einsle, O., Jung, M.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d7n OCA], [http://pdbe.org/5d7n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d7n RCSB], [http://www.ebi.ac.uk/pdbsum/5d7n PDBsum]</span></td></tr>
-
Description:
+
</table>
-
[[Category: Unreleased Structures]]
+
== Function ==
-
[[Category: Rumpf, T]]
+
[[http://www.uniprot.org/uniprot/SIR3_HUMAN SIR3_HUMAN]] NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.<ref>PMID:16788062</ref> <ref>PMID:18680753</ref> <ref>PMID:18794531</ref> <ref>PMID:19535340</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Einsle, O]]
[[Category: Gerhardt, S]]
[[Category: Gerhardt, S]]
[[Category: Jung, M]]
[[Category: Jung, M]]
-
[[Category: Einsle, O]]
+
[[Category: Rumpf, T]]
 +
[[Category: Deacylase]]
 +
[[Category: Hydrolase]]
 +
[[Category: Sirtuin 3]]

Revision as of 16:17, 2 December 2015

Crystal structure of human Sirt3 at an improved resolution

5d7n, resolution 1.83Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5d7n"
Personal tools