14-3-3 protein

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== Function ==
== Function ==
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'''14-3-3 proteins''' (PRS) are conserved regulatory proteins which bind to a multitude of signaling proteins like kinases phosphatases and transmembrane receptors. The name 14-3-3 derives from their elution pattern via chromatography.
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'''14-3-3 proteins''' (PRS) are conserved regulatory proteins which bind to a multitude of signaling proteins like kinases phosphatases and transmembrane receptors. The name 14-3-3 derives from their elution pattern via chromatography.<ref>PMID:15857576</ref>
== Disease ==
== Disease ==

Revision as of 10:41, 3 December 2015

Structure of human 14-3-3 protein ζ with phosphopeptide (yellow) (PDB code 1qja).

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3D structures of 14-3-3 proteins (Updated on 03-December-2015)

References

  1. Benzinger A, Popowicz GM, Joy JK, Majumdar S, Holak TA, Hermeking H. The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization. Cell Res. 2005 Apr;15(4):219-27. PMID:15857576 doi:10.1038/sj.cr.7290290

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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