1aih
From Proteopedia
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|PDB= 1aih |SIZE=350|CAPTION= <scene name='initialview01'>1aih</scene>, resolution 2.5Å | |PDB= 1aih |SIZE=350|CAPTION= <scene name='initialview01'>1aih</scene>, resolution 2.5Å | ||
|SITE= <scene name='pdbsite=ACA:Active+Site'>ACA</scene>, <scene name='pdbsite=ACB:Active+Site'>ACB</scene>, <scene name='pdbsite=ACC:Active+Site'>ACC</scene> and <scene name='pdbsite=ACD:Active+Site'>ACD</scene> | |SITE= <scene name='pdbsite=ACA:Active+Site'>ACA</scene>, <scene name='pdbsite=ACB:Active+Site'>ACB</scene>, <scene name='pdbsite=ACC:Active+Site'>ACC</scene> and <scene name='pdbsite=ACD:Active+Site'>ACD</scene> | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= GENBANK U24159 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10690 Haemophilus phage HP1]) | |GENE= GENBANK U24159 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10690 Haemophilus phage HP1]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aih OCA], [http://www.ebi.ac.uk/pdbsum/1aih PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1aih RCSB]</span> | ||
}} | }} | ||
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[[Category: Scocca, J J.]] | [[Category: Scocca, J J.]] | ||
[[Category: Waninger, S.]] | [[Category: Waninger, S.]] | ||
| - | [[Category: MG]] | ||
| - | [[Category: SO4]] | ||
[[Category: dna integration]] | [[Category: dna integration]] | ||
[[Category: recombination]] | [[Category: recombination]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:40:55 2008'' |
Revision as of 15:41, 30 March 2008
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| , resolution 2.5Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | , , and | ||||||
| Ligands: | , | ||||||
| Gene: | GENBANK U24159 (Haemophilus phage HP1) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CATALYTIC DOMAIN OF BACTERIOPHAGE HP1 INTEGRASE
Overview
HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenzae. The isolated C-terminal domain (residues 165-337) of the protein interacts with the recombination site and contains the four catalytic residues conserved in the integrase family. This domain represents a novel fold consisting principally of well-packed alpha helices, a surface beta sheet, and an ordered 17-residue C-terminal tail. The conserved triad of basic residues and the active-site tyrosine are contributed by a single monomer and occupy fixed positions in a defined active-site cleft. Dimers are formed by mutual interactions of the tail of one monomer with an adjacent monomer; this orients active-site clefts antiparallel to each other.
About this Structure
1AIH is a Single protein structure of sequence from Haemophilus phage hp1. Full crystallographic information is available from OCA.
Reference
Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution., Hickman AB, Waninger S, Scocca JJ, Dyda F, Cell. 1997 Apr 18;89(2):227-37. PMID:9108478
Page seeded by OCA on Sun Mar 30 18:40:55 2008
