Cephalosporin acylase
From Proteopedia
(Difference between revisions)
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| - | {{STRUCTURE_1jvz| PDB=1jvz | SIZE= | + | {{STRUCTURE_1jvz| PDB=1jvz | SIZE=350| SCENE= |right|CAPTION=Cephalosporin acylase α subunit (grey) and β subunit (green) complex with glutaryl 7-amino-cephalosporanic acid, [[1jvz]] }} |
'''Cephalosporin acylase''' (CSA) catalyzes the conversion of cephalosporin C (CPC) to 7-amino-cephalosporanic acid (7-ACA). CSA contains 2 non-identical subunits. CSA is used commercially for production of semi-synthetic cephalosporin antibiotics. The active site pocket of CSA is similar to that of penicillin acylase. CSA precursor is cleaved at 2 sites forming the active heterodimer. | '''Cephalosporin acylase''' (CSA) catalyzes the conversion of cephalosporin C (CPC) to 7-amino-cephalosporanic acid (7-ACA). CSA contains 2 non-identical subunits. CSA is used commercially for production of semi-synthetic cephalosporin antibiotics. The active site pocket of CSA is similar to that of penicillin acylase. CSA precursor is cleaved at 2 sites forming the active heterodimer. | ||
| - | + | </StructureSection> | |
==3D structures of cephalosporin acylase== | ==3D structures of cephalosporin acylase== | ||
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**[[1jw0]] - BdCSA + glutarate | **[[1jw0]] - BdCSA + glutarate | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:48, 6 December 2015
Template:STRUCTURE 1jvz
Cephalosporin acylase (CSA) catalyzes the conversion of cephalosporin C (CPC) to 7-amino-cephalosporanic acid (7-ACA). CSA contains 2 non-identical subunits. CSA is used commercially for production of semi-synthetic cephalosporin antibiotics. The active site pocket of CSA is similar to that of penicillin acylase. CSA precursor is cleaved at 2 sites forming the active heterodimer. </StructureSection>
3D structures of cephalosporin acylase
Updated on 06-December-2015
