Cephalosporin acylase
From Proteopedia
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| + | <StructureSection load='1jvz' size='350' side='right' caption='Cephalosporin acylase α subunit (grey) and β subunit (green) complex with glutaryl 7-amino-cephalosporanic acid (PDB entry [[1jvz]])' scene=''> | ||
'''Cephalosporin acylase''' (CSA) catalyzes the conversion of cephalosporin C (CPC) to 7-amino-cephalosporanic acid (7-ACA). CSA contains 2 non-identical subunits. CSA is used commercially for production of semi-synthetic cephalosporin antibiotics. The active site pocket of CSA is similar to that of penicillin acylase. CSA precursor is cleaved at 2 sites forming the active heterodimer. | '''Cephalosporin acylase''' (CSA) catalyzes the conversion of cephalosporin C (CPC) to 7-amino-cephalosporanic acid (7-ACA). CSA contains 2 non-identical subunits. CSA is used commercially for production of semi-synthetic cephalosporin antibiotics. The active site pocket of CSA is similar to that of penicillin acylase. CSA precursor is cleaved at 2 sites forming the active heterodimer. | ||
Revision as of 09:51, 6 December 2015
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3D structures of cephalosporin acylase
Updated on 06-December-2015
