1aol
From Proteopedia
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|PDB= 1aol |SIZE=350|CAPTION= <scene name='initialview01'>1aol</scene>, resolution 2.0Å | |PDB= 1aol |SIZE=350|CAPTION= <scene name='initialview01'>1aol</scene>, resolution 2.0Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> | + | |LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aol OCA], [http://www.ebi.ac.uk/pdbsum/1aol PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1aol RCSB]</span> | ||
}} | }} | ||
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[[Category: Hamson, C A.]] | [[Category: Hamson, C A.]] | ||
[[Category: Kim, P S.]] | [[Category: Kim, P S.]] | ||
| - | [[Category: NAG]] | ||
| - | [[Category: ZN]] | ||
[[Category: coat protein]] | [[Category: coat protein]] | ||
[[Category: retrovirus]] | [[Category: retrovirus]] | ||
[[Category: viral glycoprotein]] | [[Category: viral glycoprotein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:44:32 2008'' |
Revision as of 15:44, 30 March 2008
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| , resolution 2.0Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
FRIEND MURINE LEUKEMIA VIRUS RECEPTOR-BINDING DOMAIN
Overview
An essential step in retrovirus infection is the binding of the virus to its receptor on a target cell. The structure of the receptor-binding domain of the envelope glycoprotein from Friend murine leukemia virus was determined to 2.0 angstrom resolution by x-ray crystallography. The core of the domain is an antiparallel beta sandwich, with two interstrand loops forming a helical subdomain atop the sandwich. The residues in the helical region, but not in the beta sandwich, are highly variable among mammalian C-type retroviruses with distinct tropisms, indicating that the helical subdomain determines the receptor specificity of the virus.
About this Structure
1AOL is a Single protein structure of sequence from Friend murine leukemia virus. Full crystallographic information is available from OCA.
Reference
Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution., Fass D, Davey RA, Hamson CA, Kim PS, Cunningham JM, Berger JM, Science. 1997 Sep 12;277(5332):1662-6. PMID:9287219
Page seeded by OCA on Sun Mar 30 18:44:32 2008
