4rma
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of the FERM domain of human ezrin== |
| - | + | <StructureSection load='4rma' size='340' side='right' caption='[[4rma]], [[Resolution|resolution]] 1.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rma]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RMA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RMA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rm8|4rm8]], [[4rm9|4rm9]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rma OCA], [http://pdbe.org/4rma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rma RCSB], [http://www.ebi.ac.uk/pdbsum/4rma PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/EZRI_HUMAN EZRI_HUMAN]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.<ref>PMID:17881735</ref> <ref>PMID:18270268</ref> <ref>PMID:19111582</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: Wilk, K | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Curmi, P M.G]] | ||
| + | [[Category: Duff, A P]] | ||
| + | [[Category: Harrop, S J]] | ||
| + | [[Category: Phang, J M]] | ||
| + | [[Category: Wilk, K E]] | ||
| + | [[Category: Erm]] | ||
| + | [[Category: Ezrin]] | ||
| + | [[Category: Ferm domain]] | ||
| + | [[Category: Membrane cytoskeleton linker]] | ||
| + | [[Category: Peptide binding protein]] | ||
Revision as of 13:45, 9 December 2015
Crystal structure of the FERM domain of human ezrin
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