5e8d
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of human epiregulin in complex with the Fab fragment of murine monoclonal antibody 9E5== |
| - | + | <StructureSection load='5e8d' size='340' side='right' caption='[[5e8d]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5e8d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E8D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5az2|5az2]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e8d OCA], [http://pdbe.org/5e8d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e8d RCSB], [http://www.ebi.ac.uk/pdbsum/5e8d PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/EREG_HUMAN EREG_HUMAN]] Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.<ref>PMID:9419975</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Mus musculus]] | ||
[[Category: Doi, H]] | [[Category: Doi, H]] | ||
| + | [[Category: Fujitani, H]] | ||
[[Category: Iijima, M]] | [[Category: Iijima, M]] | ||
| - | [[Category: | + | [[Category: Inoue, T]] |
| + | [[Category: Kado, Y]] | ||
[[Category: Kawamura, T]] | [[Category: Kawamura, T]] | ||
| - | [[Category: Miyafusa, T]] | ||
[[Category: Kodama, T]] | [[Category: Kodama, T]] | ||
| + | [[Category: Lee, Y H]] | ||
[[Category: Matsumura, H]] | [[Category: Matsumura, H]] | ||
| - | [[Category: | + | [[Category: Miyafusa, T]] |
| - | + | ||
| - | + | ||
[[Category: Mizohata, E]] | [[Category: Mizohata, E]] | ||
| - | [[Category: | + | [[Category: Nagatoishi, S]] |
[[Category: Nakayama, T]] | [[Category: Nakayama, T]] | ||
| + | [[Category: Shibasaki, Y]] | ||
| + | [[Category: Shinoda, K]] | ||
[[Category: Sugiyama, A]] | [[Category: Sugiyama, A]] | ||
| - | [[Category: | + | [[Category: Tsumoto, K]] |
| + | [[Category: Yoshizumi, T]] | ||
| + | [[Category: Antibody]] | ||
| + | [[Category: Cancer]] | ||
| + | [[Category: Epidermal growth factor]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Immunoglobulin]] | ||
| + | [[Category: Monoclonal antibody]] | ||
Revision as of 13:49, 9 December 2015
Crystal structure of human epiregulin in complex with the Fab fragment of murine monoclonal antibody 9E5
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Categories: Mus musculus | Doi, H | Fujitani, H | Iijima, M | Inoue, T | Kado, Y | Kawamura, T | Kodama, T | Lee, Y H | Matsumura, H | Miyafusa, T | Mizohata, E | Nagatoishi, S | Nakayama, T | Shibasaki, Y | Shinoda, K | Sugiyama, A | Tsumoto, K | Yoshizumi, T | Antibody | Cancer | Epidermal growth factor | Immune system | Immunoglobulin | Monoclonal antibody
