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5elh
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of mouse Unkempt zinc fingers 1-3 (ZnF1-3), bound to RNA== |
| - | + | <StructureSection load='5elh' size='340' side='right' caption='[[5elh]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5elh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ELH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ELH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5elk|5elk]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5elh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5elh OCA], [http://pdbe.org/5elh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5elh RCSB], [http://www.ebi.ac.uk/pdbsum/5elh PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/UNK_MOUSE UNK_MOUSE]] Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280).<ref>PMID:25737280</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Murn, J]] | ||
| + | [[Category: Patel, D J]] | ||
[[Category: Shi, Y]] | [[Category: Shi, Y]] | ||
| + | [[Category: Teplova, M]] | ||
[[Category: Zarnack, K]] | [[Category: Zarnack, K]] | ||
| - | [[Category: | + | [[Category: Ccch zinc finger]] |
| + | [[Category: Rna binding protein-rna complex]] | ||
| + | [[Category: Rna-binding protein]] | ||
| + | [[Category: Unkempt]] | ||
Revision as of 13:50, 9 December 2015
Crystal structure of mouse Unkempt zinc fingers 1-3 (ZnF1-3), bound to RNA
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