Cruzain
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='1me3' size='400' side='right' caption='Structure of cruzain complex with methylketone inhibitor (PDB entry [[1me3]])' scene=''> | ||
| - | '''Cruzain''' (Cru) is the major cysteine protease present in ''Trypanosoma cruzi'' which is the parasite causing Chagas disease. | ||
| + | <StructureSection load='1me3' size='350' side='right' caption='Structure of cruzain complex with methylketone inhibitor (PDB entry [[1me3]])' scene=''> | ||
| + | |||
| + | '''Cruzain''' (Cru) is the major cysteine protease present in ''Trypanosoma cruzi'' which is the parasite causing Chagas disease. <ref>PMID:11742345</ref> | ||
| + | </StructureSection> | ||
==3D structures of cruzain== | ==3D structures of cruzain== | ||
| Line 11: | Line 13: | ||
[[1ewl]], [[1ewm]] – Cru catalytic domain + methylbutane inhibitor<br /> | [[1ewl]], [[1ewm]] – Cru catalytic domain + methylbutane inhibitor<br /> | ||
[[1ewp]] - Cru catalytic domain + MOR-Leu-HPQ<br /> | [[1ewp]] - Cru catalytic domain + MOR-Leu-HPQ<br /> | ||
| + | == References == | ||
| + | <references/> | ||
| - | </StructureSection> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:03, 15 December 2015
| |||||||||||
3D structures of cruzain
Updated on 15-December-2015
1aim, 2aim, 1me3, 1me4 – Cru catalytic domain + methylketone inhibitor – Trypanosoma cruzi
1f29, 1f2a, 1f2b, 1f2c, 1ewo, 3lxs - Cru catalytic domain + vinyl sulfone derived inhibitor
1ewl, 1ewm – Cru catalytic domain + methylbutane inhibitor
1ewp - Cru catalytic domain + MOR-Leu-HPQ
References
- ↑ Larsen NA, Turner JM, Stevens J, Rosser SJ, Basran A, Lerner RA, Bruce NC, Wilson IA. Crystal structure of a bacterial cocaine esterase. Nat Struct Biol. 2002 Jan;9(1):17-21. PMID:11742345 doi:10.1038/nsb742
