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Crystallin

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{{STRUCTURE_2g98| PDB=2g98 | SIZE=300| SCENE=Crystalline/C/1 |right|CAPTION=human γ-D-crystalline, [[2g98]] }}
{{STRUCTURE_2g98| PDB=2g98 | SIZE=300| SCENE=Crystalline/C/1 |right|CAPTION=human γ-D-crystalline, [[2g98]] }}
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== Function ==
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'''Crystalline''' is found in the lens of the eye accounting for the transparency and probably increasing the refractive index of it. α-, β-, γ-, δ-crystalline are named according to the order they are eluted by gel filtration. δ-crystalline is found in avian and reptilian lenses.
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'''Crystalline''' is found in the lens of the eye accounting for the transparency and probably increasing the refractive index of it. α-, β-, γ-, δ-crystalline are named according to the order they are eluted by gel filtration. δ-crystalline is found in avian and reptilian lenses.<ref>PMID:12729747</ref>
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[[1elp]] - γ-D-crystalline – bovine<br />
[[1elp]] - γ-D-crystalline – bovine<br />
[[1auw]] - δ-2-crystalline (mutant) - duck
[[1auw]] - δ-2-crystalline (mutant) - duck
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:40, 15 December 2015

Template:STRUCTURE 2g98

Function

Crystalline is found in the lens of the eye accounting for the transparency and probably increasing the refractive index of it. α-, β-, γ-, δ-crystalline are named according to the order they are eluted by gel filtration. δ-crystalline is found in avian and reptilian lenses.[1]



3D Structures of Crystalline

Updated on 15-December-2015

2g98 - hγ-D-crystalline – human
1h4a - hγ-D-crystalline (mutant)
1elp - γ-D-crystalline – bovine
1auw - δ-2-crystalline (mutant) - duck

References

  1. Basak A, Bateman O, Slingsby C, Pande A, Asherie N, Ogun O, Benedek GB, Pande J. High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract. J Mol Biol. 2003 May 16;328(5):1137-47. PMID:12729747

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Michal Harel, Alexander Berchansky, Jaime Prilusky

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