1aw6

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|PDB= 1aw6 |SIZE=350|CAPTION= <scene name='initialview01'>1aw6</scene>
|PDB= 1aw6 |SIZE=350|CAPTION= <scene name='initialview01'>1aw6</scene>
|SITE= <scene name='pdbsite=CD4:Cd+Binding+Site'>CD4</scene> and <scene name='pdbsite=CD5:Cd+Binding+Site'>CD5</scene>
|SITE= <scene name='pdbsite=CD4:Cd+Binding+Site'>CD4</scene> and <scene name='pdbsite=CD5:Cd+Binding+Site'>CD5</scene>
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|LIGAND= <scene name='pdbligand=CD:CADMIUM ION'>CD</scene>
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|LIGAND= <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
 +
|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aw6 OCA], [http://www.ebi.ac.uk/pdbsum/1aw6 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1aw6 RCSB]</span>
}}
}}
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[[Category: Baleja, J D.]]
[[Category: Baleja, J D.]]
[[Category: Wagner, G.]]
[[Category: Wagner, G.]]
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[[Category: CD]]
 
[[Category: dna-binding]]
[[Category: dna-binding]]
[[Category: transcription regulation]]
[[Category: transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:03:04 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:48:45 2008''

Revision as of 15:48, 30 March 2008


PDB ID 1aw6

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Sites: and
Ligands:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



GAL4 (CD), NMR, 24 STRUCTURES


Overview

We have refined the solution structure of cadmium-bound GAL4 and present its 15N and 1H NMR assignments. The root-mean-square (rms) deviation to the average structure was 0.4 +/- 0.05 A for backbone atoms, and 0.9 +/- 0.1 A for all heavy atoms. The three-bond heteronuclear 3J(113Cd,1H) coupling constants were found to disobey a Karplus-type relationship, which was attributable to the unusual constraints imposed by the bimetal-thiolate cluster in GAL4. We conclude that the structural parameters that correlate to 3J(113Cd,1H) are complex.

About this Structure

1AW6 is a Single protein structure of sequence from Saccharomyces cerevisiae. This structure supersedes the now removed PDB entry 125D. Full crystallographic information is available from OCA.

Reference

Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination., Baleja JD, Thanabal V, Wagner G, J Biomol NMR. 1997 Dec;10(4):397-401. PMID:9460244

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