4r9y
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal structure of KKOFab in complex with platelet factor 4== |
| - | + | <StructureSection load='4r9y' size='340' side='right' caption='[[4r9y]], [[Resolution|resolution]] 4.11Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4r9y]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R9Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r97|4r97]], [[4r9w|4r9w]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r9y OCA], [http://pdbe.org/4r9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r9y RCSB], [http://www.ebi.ac.uk/pdbsum/4r9y PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/PLF4_HUMAN PLF4_HUMAN]] Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.<ref>PMID:7644496</ref> |
| - | [[ | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Cai, Z]] | [[Category: Cai, Z]] | ||
| + | [[Category: Greene, M I]] | ||
| + | [[Category: Liu, Q]] | ||
[[Category: Zhu, Z]] | [[Category: Zhu, Z]] | ||
| + | [[Category: Antibody]] | ||
| + | [[Category: Antigen]] | ||
| + | [[Category: Blood]] | ||
| + | [[Category: Cxc chemokine]] | ||
| + | [[Category: Hit]] | ||
| + | [[Category: Immune system-cytokine complex]] | ||
| + | [[Category: Immunoglobulin]] | ||
| + | [[Category: Kko]] | ||
| + | [[Category: Pf4]] | ||
Revision as of 13:53, 16 December 2015
Crystal structure of KKOFab in complex with platelet factor 4
| |||||||||||
Categories: Cai, Z | Greene, M I | Liu, Q | Zhu, Z | Antibody | Antigen | Blood | Cxc chemokine | Hit | Immune system-cytokine complex | Immunoglobulin | Kko | Pf4
