Cytidine monophosphate kinase
From Proteopedia
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<StructureSection load='3w8n' size='350' side='right' caption='Structure of cytidine monophosphate kinase complex with CMP (stick model) (PDB entry [[3w8n]])' scene=''> | <StructureSection load='3w8n' size='350' side='right' caption='Structure of cytidine monophosphate kinase complex with CMP (stick model) (PDB entry [[3w8n]])' scene=''> | ||
| - | '''Cytidine monophosphate kinase''' (CMK) catalyzes the reversible conversion of CMP and ATP to CDP and ADP. <ref>PMID: | + | '''Cytidine monophosphate kinase''' (CMK) catalyzes the reversible conversion of CMP and ATP to CDP and ADP. <ref>PMID:9862805</ref> |
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| + | == Relevance == | ||
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| + | CMK from bacterial pathogens is a target for new antibiotics development. | ||
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</StructureSection> | </StructureSection> | ||
Revision as of 09:09, 17 December 2015
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3D structures of cytidine monophosphate kinase
(Updated on 17-December-2015)
References
- ↑ Briozzo P, Golinelli-Pimpaneau B, Gilles AM, Gaucher JF, Burlacu-Miron S, Sakamoto H, Janin J, Barzu O. Structures of escherichia coli CMP kinase alone and in complex with CDP: a new fold of the nucleoside monophosphate binding domain and insights into cytosine nucleotide specificity. Structure. 1998 Dec 15;6(12):1517-27. PMID:9862805
