Sandbox T4SS

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VirB is made up of 11 different VirB proteins systhesized from the ''virB'' operon. Most T4SS have homologes of these 12 proteins (11 from VirB and 1 from VirD)
VirB is made up of 11 different VirB proteins systhesized from the ''virB'' operon. Most T4SS have homologes of these 12 proteins (11 from VirB and 1 from VirD)
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[[Image:Janeyuan1.1.png|thumb|Overview of T4SS structures<ref name="one" />]]
VirB7, VirB7 and VirB10 initiate the assembly of the core of the T4SS. The complex forms spontaneously with out the input of external energy like ATP. [[Image:Janeyuan1.2.png|thumb|Overview of formation of T4SS<ref name="one" />]]
VirB7, VirB7 and VirB10 initiate the assembly of the core of the T4SS. The complex forms spontaneously with out the input of external energy like ATP. [[Image:Janeyuan1.2.png|thumb|Overview of formation of T4SS<ref name="one" />]]
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[[Image:Janeyuan1.1.png|thumb|Overview of T4SS structures<ref name="one" />]]
 
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Revision as of 19:04, 17 December 2015

This page is setup for Jian to build her senior project for OU CHEM 4923

FUNCTIONS OF TYPE 4 SECRETION SYSTEMS

PDB ID 1gki

Drag the structure with the mouse to rotate

References

  1. 1.0 1.1 1.2 Wallden K, Rivera-Calzada A, Waksman G. Type IV secretion systems: versatility and diversity in function. Cell Microbiol. 2010 Sep 1;12(9):1203-12. doi: 10.1111/j.1462-5822.2010.01499.x. , Epub 2010 Jul 16. PMID:20642798 doi:http://dx.doi.org/10.1111/j.1462-5822.2010.01499.x
  2. Christie PJ, Whitaker N, Gonzalez-Rivera C. Mechanism and structure of the bacterial type IV secretion systems. Biochim Biophys Acta. 2014 Aug;1843(8):1578-91. doi:, 10.1016/j.bbamcr.2013.12.019. Epub 2014 Jan 2. PMID:24389247 doi:http://dx.doi.org/10.1016/j.bbamcr.2013.12.019
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