This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Core-binding factor
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Function == | == Function == | ||
| - | '''Core-binding factor''' (CBF) is a heterodimeric transcription factor which is composed of α chain which binds DNA and a regulatory β chain. CBF binds to various enhancers and promoters including murine leukemia virus and polyomavirus enhancer. <ref>PMID:11276260</ref> | + | '''Core-binding factor''' (CBF) is a heterodimeric transcription factor which is composed of <scene name='70/708082/Cv/2'>α chain which binds DNA and a regulatory β chain</scene>. CBF binds to various enhancers and promoters including murine leukemia virus and polyomavirus enhancer. <ref>PMID:11276260</ref> |
== Disease == | == Disease == | ||
Revision as of 08:48, 21 December 2015
| |||||||||||
3D Structures of core-binding factor
Updated on 21-December-2015
References
- ↑ Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260 doi:http://dx.doi.org/10.1038/86264
