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Dehalogenase

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'''Dehalogenases''' catalyze the removal of halogen atom from substrates.<br />
'''Dehalogenases''' catalyze the removal of halogen atom from substrates.<br />
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• '''Haloalkane dehalogenase''' converts haloalkanes to alcohol<br />
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• '''Haloalkane dehalogenase''' converts haloalkanes to alcohol<ref>PMID:21294712</ref><br />
• '''Halohydrin dehalogenase''' converts halohydrins to epoxide<br />
• '''Halohydrin dehalogenase''' converts halohydrins to epoxide<br />
• '''L-2 haloacid dehalogenase''' converts L-2-haloacids to D-2-hydroxyacid<br />
• '''L-2 haloacid dehalogenase''' converts L-2-haloacids to D-2-hydroxyacid<br />
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== Relevance ==
== Relevance ==
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Haloalkane dehalogenase is tested for the biodegredation of toxic industrial by-products.
== Structural highlights ==
== Structural highlights ==

Revision as of 10:19, 22 December 2015

Structure of haloalkane dehalogenase complex with I- ion (purple) (PDB code 2edc).

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3D structures of dehalogenase

Updated on 22-December-2015


References

  1. ↑ Koudelakova T, Chovancova E, Brezovsky J, Monincova M, Fortova A, Jarkovsky J, Damborsky J. Substrate specificity of haloalkane dehalogenases. Biochem J. 2011 Apr 15;435(2):345-54. doi: 10.1042/BJ20101405. PMID:21294712 doi:http://dx.doi.org/10.1042/BJ20101405

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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