4x46

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'''Unreleased structure'''
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==X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A==
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<StructureSection load='4x46' size='340' side='right' caption='[[4x46]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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The entry 4x46 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4x46]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X46 FirstGlance]. <br>
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Authors: Balaev, V.V., Lashkov, A.A., Prokofev, I.I., Gabdoulkhakov, A.G., Betzel, C., Mikhailov, A.M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] </span></td></tr>
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Description: X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x46 OCA], [http://pdbe.org/4x46 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x46 RCSB], [http://www.ebi.ac.uk/pdbsum/4x46 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Prokofev, I.I]]
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== Function ==
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[[http://www.uniprot.org/uniprot/TYPH_SALTY TYPH_SALTY]] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
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__TOC__
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</StructureSection>
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[[Category: Thymidine phosphorylase]]
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[[Category: Balaev, V V]]
[[Category: Betzel, C]]
[[Category: Betzel, C]]
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[[Category: Mikhailov, A.M]]
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[[Category: Gabdoulkhakov, A G]]
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[[Category: Lashkov, A.A]]
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[[Category: Lashkov, A A]]
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[[Category: Balaev, V.V]]
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[[Category: Mikhailov, A M]]
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[[Category: Gabdoulkhakov, A.G]]
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[[Category: Prokofev, I I]]
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[[Category: Metabolism]]
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[[Category: Nucleoside]]
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[[Category: Transferase]]

Revision as of 12:45, 23 December 2015

X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A

4x46, resolution 2.20Å

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