Dethiobiotin synthetase
From Proteopedia
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| - | <StructureSection load='1a82' size=' | + | <StructureSection load='1a82' size='450' side='right' caption='Dethiobiotin synthetase complex with dethiobiotin, ATP and Mg+2 ion (green) (PDB entry [[1a82]])' scene='49/493028/Cv/1'> |
'''Dethiobiotin synthetase''' (DTBS) catalyzes the first ring closure in the biotin synthesis. The reaction transforms 7,8-diaminononanoate (DAN), ATP and CO2 to dethiobiotin (DTB), ADP and phosphate.<ref>PMID:4921568</ref> | '''Dethiobiotin synthetase''' (DTBS) catalyzes the first ring closure in the biotin synthesis. The reaction transforms 7,8-diaminononanoate (DAN), ATP and CO2 to dethiobiotin (DTB), ADP and phosphate.<ref>PMID:4921568</ref> | ||
Revision as of 12:14, 29 December 2015
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3D dethiobiotin synthetase
Updated on 29-December-2015
References
- ↑ Krell K, Eisenberg MA. The purification and properties of dethiobiotin synthetase. J Biol Chem. 1970 Dec 25;245(24):6558-66. PMID:4921568
- ↑ Kack H, Gibson KJ, Lindqvist Y, Schneider G. Snapshot of a phosphorylated substrate intermediate by kinetic crystallography. Proc Natl Acad Sci U S A. 1998 May 12;95(10):5495-500. PMID:9576910
