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Diphtheria toxin repressor

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<StructureSection load='1c0w' size='350' side='right' caption='Structure of diphtheria toxin repressor complex with DNA and Co+2 ion (PDB entry [[1c0w]])' scene=''>
<StructureSection load='1c0w' size='350' side='right' caption='Structure of diphtheria toxin repressor complex with DNA and Co+2 ion (PDB entry [[1c0w]])' scene=''>
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'''Diphtheria toxin repressor''' (DtxR) is an iron-dependent repressor which is synthesized by the diphtheria bacterium when it is in iron-poor environment. DtxR structure contains a DNA-binding domain (DBD) containing the hlix-turn-helix motif at the N-terminal, an interface domain containing the metal-binding sites and a flexible C-terminal. The DtxR regulates the expression of high affinity iron uptake system.
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'''Diphtheria toxin repressor''' (DtxR) is an iron-dependent repressor which is synthesized by the diphtheria bacterium when it is in iron-poor environment. The DtxR regulates the expression of high affinity iron uptake system. <ref>PMID:12675807</ref>
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== Structural highlights ==
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DtxR structure contains a DNA-binding domain (DBD) containing the helix-turn-helix motif at the N-terminal, an interface domain containing the metal-binding sites and a flexible C-terminal.
</StructureSection>
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**[[1c0w]] – CdDtxR + Co + DNA<br />
**[[1c0w]] – CdDtxR + Co + DNA<br />
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 13:10, 30 December 2015

Structure of diphtheria toxin repressor complex with DNA and Co+2 ion (PDB entry 1c0w)

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3D structures of diphtheria toxin repressor

Updated on 30-December-2015

References

  1. Guedon E, Helmann JD. Origins of metal ion selectivity in the DtxR/MntR family of metalloregulators. Mol Microbiol. 2003 Apr;48(2):495-506. PMID:12675807

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