2na0
From Proteopedia
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| - | + | ==NMR structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) mutant V77E in a Ca2+-free/Mg2+-bound Activator State== | |
| - | + | <StructureSection load='2na0' size='340' side='right' caption='[[2na0]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2na0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NA0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2na0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2na0 OCA], [http://pdbe.org/2na0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2na0 RCSB], [http://www.ebi.ac.uk/pdbsum/2na0 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[Category: Ames, J | + | [[http://www.uniprot.org/uniprot/GUC1A_BOVIN GUC1A_BOVIN]] Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure. |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ames, J B]] | ||
[[Category: Lim, S]] | [[Category: Lim, S]] | ||
| + | [[Category: Activator state]] | ||
| + | [[Category: Lyase activator]] | ||
| + | [[Category: Signal transduction]] | ||
Revision as of 19:34, 30 December 2015
NMR structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) mutant V77E in a Ca2+-free/Mg2+-bound Activator State
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