CCL2

The chemokine (C-C motif) ligand (CCL2), also known as :

- monocyte chemotactic protein 1 (MCP1) - small inducible cytokine A2 (SCYA2) - MCAF - GDCF-2 - SMC-CF - HSMCR30 - MGC9434 - GDCF-2 - HC11.

Function

Disease

Relevance

Structural highlights

CCL2 belongs to the superfamily of chemokines, which are proteins involved in immunoregulatory and inflammatory processes. The superfamily can be subdivided into 4 smaller groups, depending on the N-ter arangment of the cysteines. CCL2 is part of the C-C motif group because of the covalent bond made between 2 of the 4 cysteines of the Nter domain.

References

https://fr.wikipedia.org/wiki/CCL2