Neuraminidase
From Proteopedia
(Difference between revisions)
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*[[User:Michael Strong/H1N1/NA]] for Influenza virus neuraminidase<br /> | *[[User:Michael Strong/H1N1/NA]] for Influenza virus neuraminidase<br /> | ||
*[[User:Michael Strong/H1N1/NA/MSA]] for multiple sequence alignment.<br /> | *[[User:Michael Strong/H1N1/NA/MSA]] for multiple sequence alignment.<br /> | ||
| - | For other inhibitors see [[Neuraminidase Inhibitor Pharmacokinetics]]. | + | For other inhibitors see<br /> |
| + | *[[Neuraminidase Inhibitor Pharmacokinetics]]<br /> | ||
| + | *[[Carbohydrate binding domain from Streprococcus pneumoniae NanA sialidase complexed with 3'-sialyllactose]]. | ||
==3D structures of Neuraminidase== | ==3D structures of Neuraminidase== | ||
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**[[2ya6]] - SpNANA catalytic domain + sialic acid analog<br /> | **[[2ya6]] - SpNANA catalytic domain + sialic acid analog<br /> | ||
**[[2jkb]] - SpNANB residues 30-697 + sialic acid analog<br /> | **[[2jkb]] - SpNANB residues 30-697 + sialic acid analog<br /> | ||
| + | **[[4c1w]] - SpNANB residues 52-236 + sialic acid derivative<br /> | ||
**[[4foq]], [[4fov]], [[4fow]], [[4foy]], [[4fp2]], [[4fp3]], [[4fpc]], [[4fpe]], [[4fpf]], [[4fpg]], [[4fph]], [[4fpj]], [[4fpk]], [[4fpl]], [[4fpo]], [[4fpy]], [[4fq4]] – SpNANB + inhibitor<br /> | **[[4foq]], [[4fov]], [[4fow]], [[4foy]], [[4fp2]], [[4fp3]], [[4fpc]], [[4fpe]], [[4fpf]], [[4fpg]], [[4fph]], [[4fpj]], [[4fpk]], [[4fpl]], [[4fpo]], [[4fpy]], [[4fq4]] – SpNANB + inhibitor<br /> | ||
**[[1w0p]] – VcNANA + sialic derivative<br /> | **[[1w0p]] – VcNANA + sialic derivative<br /> | ||
Revision as of 16:21, 5 January 2016
Neuraminidase (NAN) cleaves the glycosidic bonds of neuraminic acid. The viral NAN is a drug target for prevention of influenza.
See also
- Avian Influenza Neuraminidase, Tamiflu and Relenza
- User:Michael Strong/H1N1/NA for Influenza virus neuraminidase
- User:Michael Strong/H1N1/NA/MSA for multiple sequence alignment.
For other inhibitors see
- Neuraminidase Inhibitor Pharmacokinetics
- Carbohydrate binding domain from Streprococcus pneumoniae NanA sialidase complexed with 3'-sialyllactose.
3D structures of Neuraminidase
Updated on 05-January-2016
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Eran Hodis
