Beta-lactamase
From Proteopedia
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'''Beta-lactamase''' (Blac) are enzymes which make bacteria resistant to β-lactam antibiotics by breaking their β-lactam ring. Blac are classified according to their resistance targets.<br /> | '''Beta-lactamase''' (Blac) are enzymes which make bacteria resistant to β-lactam antibiotics by breaking their β-lactam ring. Blac are classified according to their resistance targets.<br /> | ||
*Class A are broad-spectrum<br /> | *Class A are broad-spectrum<br /> | ||
| - | *Class B are metalloenzymes<br /> | + | *Class B are metalloenzymes. See also [[Class C beta-lactamase]].<br /> |
*Class C are cephalosporinases<br /> | *Class C are cephalosporinases<br /> | ||
*Class D are cloxacilanases<br /> | *Class D are cloxacilanases<br /> | ||
Revision as of 16:45, 5 January 2016
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3D Structures of Beta-lactamase
Updated on 05-January-2016
References
- ↑ King D, Strynadka N. Crystal structure of New Delhi metallo-beta-lactamase reveals molecular basis for antibiotic resistance. Protein Sci. 2011 Sep;20(9):1484-91. doi: 10.1002/pro.697. Epub 2011 Aug, 2. PMID:21774017 doi:10.1002/pro.697
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