Cyclin-dependent kinase regulatory subunit

(Difference between revisions)

Revision as of 17:33, 5 January 2016

Updated on 05-January-2016

↑ Upton RN, Huang YF. Influence of cardiac output, injection time and injection volume on the initial mixing of drugs with venous blood after i.v. bolus administration to sheep. Br J Anaesth. 1993 Mar;70(3):333-8. PMID:8471379

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 <StructureSection load='1dks' size='340' side='right' caption='Human CKS-1 complex with phosphate (PDB code [[1dks]])' scene=''>
-'''Cyclin-dependent kinase regulatory subunit''' (CKS) is a small protein which is essential for the functioning of CDK-cyclin complex.  CKS binds to the catalytic subunit of CDK see complex structure in <scene name='71/715441/Pdb4yc6/1'>pdb 4yc6</scene> where CDK1 is in grey, pink, magenta and gold and CKS1 i in green, yellow, cyan and red.  CKS1 is essential for CDK5 functioning in neuronal diferentiation.  CKS exists as hexamer of homodimers and can bind six kinase molecules.
+'''Cyclin-dependent kinase regulatory subunit''' (CKS) is a small protein which is essential for the functioning of CDK-cyclin complex.  CKS binds to the catalytic subunit of CDK see complex structure in <scene name='71/715441/Pdb4yc6/1'>pdb 4yc6</scene> where CDK1 is in grey, pink, magenta and gold and CKS1 i in green, yellow, cyan and red.  CKS1 is essential for CDK5 functioning in neuronal differentiation.<ref>PMID:8471379</ref>
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 == Structural highlights ==
+CKS exists as hexamer of homodimers and can bind six kinase molecules.
 </StructureSection>