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1bev
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 1bev |SIZE=350|CAPTION= <scene name='initialview01'>1bev</scene>, resolution 3.0Å | |PDB= 1bev |SIZE=350|CAPTION= <scene name='initialview01'>1bev</scene>, resolution 3.0Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bev OCA], [http://www.ebi.ac.uk/pdbsum/1bev PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1bev RCSB]</span> | ||
}} | }} | ||
| Line 28: | Line 31: | ||
[[Category: Stuart, D.]] | [[Category: Stuart, D.]] | ||
[[Category: Tate, J.]] | [[Category: Tate, J.]] | ||
| - | [[Category: MYR]] | ||
| - | [[Category: SO4]] | ||
[[Category: bovine enterovirus vg-5-27]] | [[Category: bovine enterovirus vg-5-27]] | ||
[[Category: coat protein]] | [[Category: coat protein]] | ||
| Line 35: | Line 36: | ||
[[Category: picornavirus]] | [[Category: picornavirus]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:59:30 2008'' |
Revision as of 15:59, 30 March 2008
| |||||||
| , resolution 3.0Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
BOVINE ENTEROVIRUS VG-5-27
Overview
We have determined the crystal structure of a bovine enterovirus, revealing that the topologies of the major capsid proteins and the overall architecture of the virion are similar to those of related picornaviruses. The external loops joining beta-strands are truncated and the canyon region is partially filled by an extension of the VP3 G-H loop giving the viral capsid a relatively smooth appearance. These changes may have implications for cell attachment. In spite of these differences the virus maintains a hydrophobic pocket within VP1, occupied by a specific 'pocket factor' which appears to be myristic acid. These observations support the proposal that a kinetic equilibrium exists between occupied and unoccupied pocket states, with occupation inhibiting uncoating.
About this Structure
1BEV is a Protein complex structure of sequences from Bovine enterovirus. Full crystallographic information is available from OCA.
Reference
Implications for viral uncoating from the structure of bovine enterovirus., Smyth M, Tate J, Hoey E, Lyons C, Martin S, Stuart D, Nat Struct Biol. 1995 Mar;2(3):224-31. PMID:7773791
Page seeded by OCA on Sun Mar 30 18:59:30 2008
