Met repressor

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'''Met repressor''' (MR) interacts with the DNA operator (Met box) repressing methionine synthesis. The corepressor of MR is S-adenosyl methionine (SAM) which is a product of methionine synthesis. Binding of SAM to MR increases the repressor affinity to the DNA thus halting methionine synthesis. For additional details see [[Joe Granger Methionine Repressor: Escherichia coli]].
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'''Met repressor''' (MR) interacts with the DNA operator (Met box) repressing methionine synthesis. The corepressor of MR is S-adenosyl methionine (SAM) which is a product of methionine synthesis. Binding of SAM to MR increases the repressor affinity to the DNA thus halting methionine synthesis. For additional details see<br />
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[[Taylor met rpressor]]<br />
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[[Joe Granger Methionine Repressor: Escherichia coli]].
== 3D Structures of Met repressor ==
== 3D Structures of Met repressor ==

Revision as of 07:12, 11 January 2016

Image:1mjo.png
EcMR (mutant) complex with corepressor SAM and DNA 2eyi

Template:STRUCTURE 1mjo












Met repressor (MR) interacts with the DNA operator (Met box) repressing methionine synthesis. The corepressor of MR is S-adenosyl methionine (SAM) which is a product of methionine synthesis. Binding of SAM to MR increases the repressor affinity to the DNA thus halting methionine synthesis. For additional details see
Taylor met rpressor
Joe Granger Methionine Repressor: Escherichia coli.

3D Structures of Met repressor

Updated on 11-January-2016

1cmb – EcMR – Escherichia coli
1mjk – EcMR (mutant)
1cma – EcMR + DNA
1mjm – EcMR (mutant) + DNA
1cmc – EcMR + SAM
1mjl, 1mjp – EcMR (mutant) + SAM
1mj2, 1mjo, 1mjq – EcMR (mutant) + SAM + DNA

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Michal Harel, Alexander Berchansky

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