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Eglin
From Proteopedia
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== Relevance == | == Relevance == | ||
| - | Eglin C and its mutants are tested as protease | + | Eglin C and its mutants are tested as protease inhibitor drugs. |
== 3D Structures of Eglin == | == 3D Structures of Eglin == | ||
Revision as of 11:07, 11 January 2016
Eglin C is a serine proteinase inhibitor isolated from leech. [1]
Relevance
Eglin C and its mutants are tested as protease inhibitor drugs.
3D Structures of Eglin
Updated on 11-January-2016
1egp – lEglin-C – leech
1egl - lEglin-C – NMR
1sbn, 1sib, 1cse - lEglin-C+BsSubtilisin – Bacillus subtilis
2sec - lEglin-C+BlSubtilisin – Bacillus licheniformis
1acb - lEglin-C+bChymotrypsinogen – bovine
4b1t, 4b2a, 4b2b, 4b2c - lEglin-C (mutant) +bTrypsin (mutant)
1mee - lEglin-C+BpMesentericopeptidase – Bacillus pumilus
2tec, 3tec, 1tec - lEglin-C+TvThermitase – Thermoactinomyces vulgaris
4h4f - lEglin-C+ hChymotrypsin – human
References
- ↑ McPhalen CA, James MN. Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo. Biochemistry. 1988 Aug 23;27(17):6582-98. PMID:3064813
