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Avidin

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The presence of additional hydrophobic and hydrophilic groups in the binding site of avidin may account for its higher affinity constant.
The presence of additional hydrophobic and hydrophilic groups in the binding site of avidin may account for its higher affinity constant.
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Unexpectedly, a residual N-acetylglucosamine moiety was detected in the deglycosylated avidin monomer. These <scene name='Sandbox-test/Ligands/1'>sugars</scene> appear along with the biotin but outside of the biotin binding pockets.
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Unexpectedly, a residual N-acetylglucosamine moiety was detected in the deglycosylated avidin monomer. These <scene name='41/410356/Cv/14'>sugars</scene> appear along with the biotin but outside of the biotin binding pockets.
See also:<br />
See also:<br />

Revision as of 13:16, 12 January 2016

The avidin tetramer complex with biotin (PDB code 2avi)

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3D structures of Avidin

Updated on 12-January-2016


Reference

  • Livnah O, Bayer EA, Wilchek M, Sussman JL. Three-dimensional structures of avidin and the avidin-biotin complex. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5076-80. PMID:8506353
  • Livnah O, Bayer EA, Wilchek M, Sussman JL. The structure of the complex between avidin and the dye, 2-(4'-hydroxyazobenzene) benzoic acid (HABA). FEBS Lett. 1993 Aug 9;328(1-2):165-8. PMID:8344421
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