1bhc
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 1bhc |SIZE=350|CAPTION= <scene name='initialview01'>1bhc</scene>, resolution 2.7Å | |PDB= 1bhc |SIZE=350|CAPTION= <scene name='initialview01'>1bhc</scene>, resolution 2.7Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=SCN:THIOCYANATE ION'>SCN</scene> | + | |LIGAND= <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bhc OCA], [http://www.ebi.ac.uk/pdbsum/1bhc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1bhc RCSB]</span> | ||
}} | }} | ||
| Line 24: | Line 27: | ||
[[Category: Hamiaux, C.]] | [[Category: Hamiaux, C.]] | ||
[[Category: Prange, T.]] | [[Category: Prange, T.]] | ||
| - | [[Category: SCN]] | ||
[[Category: protease inhibitor]] | [[Category: protease inhibitor]] | ||
[[Category: trypsin]] | [[Category: trypsin]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:01:01 2008'' |
Revision as of 16:01, 30 March 2008
| |||||||
| , resolution 2.7Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
BOVINE PANCREATIC TRYPSIN INHIBITOR CRYSTALLIZED FROM THIOCYANATE
Overview
The structure of a monoclinic form of bovine pancreatic trypsin inhibitor (BPTI) crystallized from a thiocyanate solution has been determined and refined at 2.7 A resolution. The space group is P21 with a = 71.56, b = 73.83, c = 64.47 A, beta = 93.9 degrees and Z = 20. The ten independent molecules were located by a multi-body molecular-replacement search as developed in the AMoRe program, starting from a single monomer model (PDB code: 6PTI). The molecular arrangement of the subunits is a decamer resulting from the combination of two orthogonal fivefold and twofold non-crystallographic axes. This builds a globular micelle-like particle which minimizes hydrophobic interactions with the solvent. The refinement was conducted with non-crystallographic symmetry constraints up to a final residual of R = 0.20 (Rfree= 0.26). The root-mean-square deviations from ideal geometry were 0.015 A and 1.6 degrees on bond distances and bond angles, respectively. Several sites for thiocyanate ions were analyzed.
About this Structure
1BHC is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
The decameric structure of bovine pancreatic trypsin inhibitor (BPTI) crystallized from thiocyanate at 2.7 A resolution., Hamiaux C, Prange T, Ries-Kautt M, Ducruix A, Lafont S, Astier JP, Veesler S, Acta Crystallogr D Biol Crystallogr. 1999 Jan;55(Pt 1):103-13. Epub 1999, Jan 1. PMID:10089400
Page seeded by OCA on Sun Mar 30 19:01:01 2008
