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Ephrin

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== Function ==
== Function ==
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'''Ephrins''' (Eph) are the membrane-bound ligands of ephrin receptors. The binding of Eph and ephrin receptors is achieved via cell-cell interaction. Eph/Eph receptor signaling regulates embryonic development, guidance of axon growth, long-term potentiation, angiogenesis and stem-cell differentiation <ref>PMID:17420126.
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'''Ephrins''' (Eph) are the membrane-bound ligands of ephrin receptors. The binding of Eph and ephrin receptors is achieved via cell-cell interaction. Eph/Eph receptor signaling regulates embryonic development, guidance of axon growth, long-term potentiation, angiogenesis and stem-cell differentiation <ref>PMID:17420126</ref>.
== Disease ==
== Disease ==

Revision as of 17:51, 19 January 2016

Structure of human ephrin-A5 receptor-binding domain (green and yellow) complex with ephrin type A receptor 2 (grey and pink) (PDB code 3mx0).

Drag the structure with the mouse to rotate

3D structures of ephrin

Updated on 19-January-2016


References

  1. Egea J, Klein R. Bidirectional Eph-ephrin signaling during axon guidance. Trends Cell Biol. 2007 May;17(5):230-8. Epub 2007 Apr 8. PMID:17420126 doi:http://dx.doi.org/10.1016/j.tcb.2007.03.004

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