Epidermal growth factor
From Proteopedia
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== Function == | == Function == | ||
| - | '''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds to its receptor ([[Epidermal Growth Factor Receptor|EGFR]]). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. | + | '''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds to its receptor ([[Epidermal Growth Factor Receptor|EGFR]]). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity.<ref>PMID:2186024</ref> Some details on EGF exon in [[EGF1]]. |
== Relevance == | == Relevance == | ||
EGFR-dependent cancers are deprived of stimulus by EGF by raising antibodies against EGF via vaccination. | EGFR-dependent cancers are deprived of stimulus by EGF by raising antibodies against EGF via vaccination. | ||
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| + | == Structural highlights == | ||
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| + | All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds. | ||
</StructureSection> | </StructureSection> | ||
Revision as of 20:05, 19 January 2016
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3D structures of epidermal growth factor
Updated on 19-January-2016
