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4uez
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH== | |
| - | + | <StructureSection load='4uez' size='340' side='right' caption='[[4uez]], [[Resolution|resolution]] 2.29Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4uez]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UEZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uee|4uee]], [[4uef|4uef]], [[4uf4|4uf4]], [[5aek|5aek]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [http://pdbe.org/4uez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [http://www.ebi.ac.uk/pdbsum/4uez PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Carboxypeptidase A]] | ||
| + | [[Category: Aviles, F X]] | ||
[[Category: Costenaro, L]] | [[Category: Costenaro, L]] | ||
[[Category: Covaleda, G]] | [[Category: Covaleda, G]] | ||
[[Category: Devel, L]] | [[Category: Devel, L]] | ||
| + | [[Category: Dive, V]] | ||
| + | [[Category: Gallego, P]] | ||
| + | [[Category: Reverter, D]] | ||
| + | [[Category: Carboxypeptidase]] | ||
| + | [[Category: Cpa1]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Phosphinic inhibitor]] | ||
Revision as of 17:10, 20 January 2016
Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH
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