4xj9
From Proteopedia
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| - | ''' | + | ==Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 5.0 in 50mM Sodium Acetate with DMSO as the cryoprotectant== |
| - | + | <StructureSection load='4xj9' size='340' side='right' caption='[[4xj9]], [[Resolution|resolution]] 1.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xj9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJ9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xj9 OCA], [http://pdbe.org/4xj9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xj9 RCSB], [http://www.ebi.ac.uk/pdbsum/4xj9 PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Exo-alpha-sialidase]] | ||
[[Category: Brear, P]] | [[Category: Brear, P]] | ||
| + | [[Category: Allosteric inhibitor]] | ||
| + | [[Category: Crystallization artefact]] | ||
| + | [[Category: Drug design]] | ||
| + | [[Category: Glycosidase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Intramolecular trans-sialidase]] | ||
| + | [[Category: Neuraminidase]] | ||
| + | [[Category: Serendipitous allosteric site]] | ||
Revision as of 17:13, 20 January 2016
Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 5.0 in 50mM Sodium Acetate with DMSO as the cryoprotectant
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