5es5

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'''Unreleased structure'''
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==Crystal structure of the initiation module of LgrA in the "open" and "closed " adenylation states==
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<StructureSection load='5es5' size='340' side='right' caption='[[5es5]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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The entry 5es5 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5es5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ES5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ES5 FirstGlance]. <br>
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Authors: Reimer, J.M., Aloise, M.N., Schmeing, T.M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5es6|5es6]], [[5es7|5es7]], [[5es8|5es8]], [[5es9|5es9]]</td></tr>
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Description:
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5es5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5es5 OCA], [http://pdbe.org/5es5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5es5 RCSB], [http://www.ebi.ac.uk/pdbsum/5es5 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Aloise, M.N]]
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== Function ==
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[[Category: Reimer, J.M]]
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[[http://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA]] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.
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[[Category: Schmeing, T.M]]
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__TOC__
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</StructureSection>
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[[Category: Aloise, M N]]
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[[Category: Reimer, J M]]
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[[Category: Schmeing, T M]]
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[[Category: Adenylation domain]]
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[[Category: Formylation domain]]
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[[Category: Ligase]]
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[[Category: Nrp]]

Revision as of 17:24, 20 January 2016

Crystal structure of the initiation module of LgrA in the "open" and "closed " adenylation states

5es5, resolution 2.80Å

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