Farnesyl diphosphate synthase
From Proteopedia
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| - | + | <StructureSection load='2opm' size='350' side='right' scene='' caption='Human farnesyl diphosphate synthase tetramer complex with lipophylic bisphosphonate inhibitor (PDB code [[2opm]]) '> | |
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to a Jmol applet. Check out the other buttons as well! | to a Jmol applet. Check out the other buttons as well! | ||
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| - | '''Farnesyl diphosphate synthase''' (FPS) also named farnesyl pyrophosphate synthase catalyzes the conversion of geranyl diphosphate (GDP) and isopentenyl diphosphate (IPP) to farnesyl diphosphate and diphosphate. | + | '''Farnesyl diphosphate synthase''' (FPS) also named farnesyl pyrophosphate synthase catalyzes the conversion of geranyl diphosphate (GDP) and isopentenyl diphosphate (IPP) to farnesyl diphosphate and diphosphate<ref>PMID:11152452</ref>. |
| - | + | </StructureSection> | |
==3D structures of farnesyl diphosphate synthase== | ==3D structures of farnesyl diphosphate synthase== | ||
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**[[3dyf]] - TbFPS + IPP + inhibitor<br /> | **[[3dyf]] - TbFPS + IPP + inhibitor<br /> | ||
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| + | == References == | ||
| + | <references/> | ||
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[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 22:50, 20 January 2016
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3D structures of farnesyl diphosphate synthase
Updated on 20-January-2016
References
- ↑ Schulbach MC, Mahapatra S, Macchia M, Barontini S, Papi C, Minutolo F, Bertini S, Brennan PJ, Crick DC. Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis. J Biol Chem. 2001 Apr 13;276(15):11624-30. Epub 2001 Jan 4. PMID:11152452 doi:http://dx.doi.org/10.1074/jbc.M007168200
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