This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Farnesyl diphosphate synthase
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | <StructureSection load='2opm' size='350' side='right' scene='' caption='Human farnesyl diphosphate synthase tetramer complex with lipophylic bisphosphonate inhibitor (PDB code [[2opm]]) '> | |
<!-- | <!-- | ||
| Line 6: | Line 6: | ||
to a Jmol applet. Check out the other buttons as well! | to a Jmol applet. Check out the other buttons as well! | ||
--> | --> | ||
| - | '''Farnesyl diphosphate synthase''' (FPS) also named farnesyl pyrophosphate synthase catalyzes the conversion of geranyl diphosphate (GDP) and isopentenyl diphosphate (IPP) to farnesyl diphosphate and diphosphate. | + | '''Farnesyl diphosphate synthase''' (FPS) also named farnesyl pyrophosphate synthase catalyzes the conversion of geranyl diphosphate (GDP) and isopentenyl diphosphate (IPP) to farnesyl diphosphate and diphosphate<ref>PMID:11152452</ref>. |
| - | + | </StructureSection> | |
==3D structures of farnesyl diphosphate synthase== | ==3D structures of farnesyl diphosphate synthase== | ||
| Line 51: | Line 51: | ||
**[[3dyf]] - TbFPS + IPP + inhibitor<br /> | **[[3dyf]] - TbFPS + IPP + inhibitor<br /> | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
| + | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 22:50, 20 January 2016
| |||||||||||
3D structures of farnesyl diphosphate synthase
Updated on 20-January-2016
References
- ↑ Schulbach MC, Mahapatra S, Macchia M, Barontini S, Papi C, Minutolo F, Bertini S, Brennan PJ, Crick DC. Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis. J Biol Chem. 2001 Apr 13;276(15):11624-30. Epub 2001 Jan 4. PMID:11152452 doi:http://dx.doi.org/10.1074/jbc.M007168200
Proteopedia Page Contributors and Editors (what is this?)
Hannah Campbell, Michal Harel, Tihitina Y Aytenfisu, Alexander Berchansky, Joel L. Sussman, Sandra B. Gabelli
