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Fatty acid-binding protein
From Proteopedia
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| + | <StructureSection load='1fe3' size='350' side='right' scene='' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '> | ||
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to a Jmol applet. Check out the other buttons as well! | to a Jmol applet. Check out the other buttons as well! | ||
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| - | '''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells | + | '''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. '''IFABP''' is intestinal; '''HFABP''' is heart-type; '''BFABP''' is brain-type; '''LFABP''' is liver-type; '''AFABP''' is adipocyte; '''LMDABP''' is from flight muscle; '''TFABP''' is from testis; '''EXFABP''' is extracellular. |
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| + | == Relevance == | ||
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| + | Some FABSs are linked to metabolic and inflammatory pathways. | ||
| + | </StructureSection> | ||
==3D structures of fatty acid-binding protein== | ==3D structures of fatty acid-binding protein== | ||
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**[[3w9k]] – FABP + fatty acid – ''Sulfolobus tokodaii''<br /> | **[[3w9k]] – FABP + fatty acid – ''Sulfolobus tokodaii''<br /> | ||
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| + | == References == | ||
| + | <references/> | ||
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[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 15:52, 21 January 2016
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3D structures of fatty acid-binding protein
Updated on 21-January-2016
References
- ↑ Chmurzynska A. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J Appl Genet. 2006;47(1):39-48. PMID:16424607 doi:http://dx.doi.org/10.1007/BF03194597
