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Ferric-binding protein
From Proteopedia
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== Function == | == Function == | ||
The process of bacterial multiplication requires the acquisition of growth-essential nutrients including iron, from the host cell. '''Ferric-binding protein''' (FBP) transfers iron across the periplasmic space from human transferrin to pathogenic bacteria<ref>PMID:7934822</ref>. | The process of bacterial multiplication requires the acquisition of growth-essential nutrients including iron, from the host cell. '''Ferric-binding protein''' (FBP) transfers iron across the periplasmic space from human transferrin to pathogenic bacteria<ref>PMID:7934822</ref>. | ||
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| - | == Disease == | ||
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| - | == Relevance == | ||
== Structural highlights == | == Structural highlights == | ||
| - | + | The Fe atom in FBS is coordinated with 2 tyrosine side chains. | |
</StructureSection> | </StructureSection> | ||
== 3D Structures of ferric-binding protein'== | == 3D Structures of ferric-binding protein'== | ||
Revision as of 19:38, 21 January 2016
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3D Structures of ferric-binding protein'
Updated on 21-January-2016
1mrp, 3od7, 3odb – HiFBP + Fe – Haemophilus influenzae
1d9v – HiFBP
1nnf, 1qvs, 1qw0, 2o68, 2o69, 2o6a, 3kn7, 3kn8 - HiFBP (mutant) + Fe
1r1n – NgFBP + oxo-Fe – Neisseria gonorrhoeae
1xc1 – NgFBP + oxo-Zr
3tyh – NgFBP + oxo-Cu
1q35 – FBP – Mannheimia haemolytica
4elo, 4elp, 4elq – TtFBP – Thermus thermophilus
4elr – TtFBP + Fe
