Fibritin

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(New page: <StructureSection load='1ox3' size='340' side='right' caption='Structure of fibritin N-terminal and foldon domains )PDB code 1ox3).' scene=''> == Function == '''Fibritin''' (Fib) is...)
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<StructureSection load='1ox3' size='340' side='right' caption='Structure of fibritin N-terminal and foldon domains (PDB code [[1ox3]]).' scene=''>
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<StructureSection load='1ox3' size='340' side='right' caption='Structure of fibritin N-terminal and foldon domains )PDB code [[1ox3]]).' scene=''>
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== Function ==
== Function ==
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'''Fibritin''' (Fib) is a strctural protein of T4 bacteriophage. Fib promotes the assembly of the long tail fibers (whiskers) and their attachment to the virus tail baseplate. Fib is also responsible for the retraction of the tail fibers in adverse environment. Fib structure is composed of N-terminal domain which is responsible for attachment to the phage, a central 500A domain made of triple-helix coiled coil and the C-terminal domain ('''foldon''') – residues 458-484 – which is the trimerization domain.
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'''Fibritin''' (Fib) is a strctural protein of T4 bacteriophage. Fib promotes the assembly of the long tail fibers (whiskers) and their attachment to the virus tail baseplate. Fib is also responsible for the retraction of the tail fibers in adverse environment<ref>PMID:9261070</ref>.
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== Disease ==
== Disease ==
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== Structural highlights ==
== Structural highlights ==
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Fib structure is composed of N-terminal domain which is responsible for attachment to the phage, a central 500A domain made of triple-helix coiled coil and the C-terminal domain ('''foldon''') – residues 458-484 – which is the trimerization domain.
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</StructureSection>
==3D structures of fibritin==
==3D structures of fibritin==

Revision as of 20:53, 21 January 2016

Structure of fibritin N-terminal and foldon domains (PDB code 1ox3).

Drag the structure with the mouse to rotate

3D structures of fibritin

Updated on 21-January-2016

2bsg, 3j2o – T4Fib – T4 bacteriophage – Cryo-EM
1aa0 – T4Fib residues 371-483 – T4 bacteriophage
1avy – T4Fib residues 413-486 (mutant)
2ww6, 2ww7, 4ncu, 4ncv, 4ncw – T4Fib foldon
1u0p – T4Fib foldon - NMR
1rfo, 2kbl – T4Fib foldon (mutant) - NMR
1ox3 – T4Fib N-terminal + foldon domains
2ibl – Fib N-terminal + foldon domains – unidentified phage
1v1h, 1v1i – Fib shaft domain/T4Fib foldon domain - Adenovirus
3a1m – T4Fib foldon/GP5C


References

  1. ↑ Tao Y, Strelkov SV, Mesyanzhinov VV, Rossmann MG. Structure of bacteriophage T4 fibritin: a segmented coiled coil and the role of the C-terminal domain. Structure. 1997 Jun 15;5(6):789-98. PMID:9261070

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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