Ferric hydroxamate uptake receptor

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== Structural highlights ==
== Structural highlights ==
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The aromatic binding pocket binds the ferrichrome and contains Fe atom.<ref>PMID:9865695</ref>
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<scene name='68/684797/Cv/2'>Ferrichrome</scene> includes <scene name='68/684797/Cv/3'>3 non-standard residues N-acetyl-N-hydroxy-L-ornithine</scene> (in cyan) and contains Fe atom. The aromatic binding pocket binds the ferrichrome.<ref>PMID:9865695</ref>
</StructureSection>
</StructureSection>
==3D structures of Ferric hydroxamate uptake receptor==
==3D structures of Ferric hydroxamate uptake receptor==

Revision as of 08:18, 26 January 2016

E. coli FhuA complex with ferrichrome and Fe+3 ion (orange) (PDB code 1by5).

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3D structures of Ferric hydroxamate uptake receptor

Updated on 26-January-2016

References

  1. Forman S, Nagiec MJ, Abney J, Perry RD, Fetherston JD. Analysis of the aerobactin and ferric hydroxamate uptake systems of Yersinia pestis. Microbiology. 2007 Jul;153(Pt 7):2332-41. PMID:17600077 doi:http://dx.doi.org/10.1099/mic.0.2006/004275-0
  2. Locher KP, Rees B, Koebnik R, Mitschler A, Moulinier L, Rosenbusch JP, Moras D. Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes. Cell. 1998 Dec 11;95(6):771-8. PMID:9865695

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