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Monocyte chemoattractant protein
From Proteopedia
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CCL2 is implicated in several diseases like psoriasis, rheumatoid arthritis and atherosclerosis. | CCL2 is implicated in several diseases like psoriasis, rheumatoid arthritis and atherosclerosis. | ||
| - | + | CCL2 is implicated in rheumatoid arthritis where they may serve to recruit macrophages and perpetuate the inflammation in the joints. MPC1 has also been found elevated in the urine of people with lupus as a sign warning of inflammation of the kidney. | |
== Relevance == | == Relevance == | ||
Revision as of 12:57, 26 January 2016
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3D structures of Monocyte chemoattractant protein
Updated on 26-January-2016
References
https://fr.wikipedia.org/wiki/CCL2 http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=1DOK http://www.uniprot.org/uniprot/P13500#interaction http://www.rcsb.org/pdb/explore/explore.do?structureId=3IFD
- ↑ Carr MW, Roth SJ, Luther E, Rose SS, Springer TA. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3652-6. PMID:8170963
- ↑ Lubkowski J, Bujacz G, Boque L, Domaille PJ, Handel TM, Wlodawer A. The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions. Nat Struct Biol. 1997 Jan;4(1):64-9. PMID:8989326
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