Sandbox Reserved 1131

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<Structure load='2NMM' size='350' frame='true' align='right' caption='Human Phosphohistidine phosphatase 1 (Homotrimer)' scene='Insert optional scene name here' />{{Sandbox_Reserved_ESBS_2015}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
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<Structure load='2NMM' size='350' frame='true' align='right' caption='Human Phosphohistidine phosphatase 1 (Homotrimer)' scene='Insert optional scene name here' /> Human Phosphohistidine phosphatase 1 {{Sandbox_Reserved_ESBS_2015}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
(Human) Phosphohistidine phosphatase 1 belongs to the Janus family, and has 2 isoforms produced by alternative splicing, and 6 transcripts.
(Human) Phosphohistidine phosphatase 1 belongs to the Janus family, and has 2 isoforms produced by alternative splicing, and 6 transcripts.

Revision as of 21:04, 28 January 2016

Human Phosphohistidine phosphatase 1 (Homotrimer)

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Human Phosphohistidine phosphatase 1
This Sandbox is Reserved from 15/12/2015, through 15/06/2016 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1120 through Sandbox Reserved 1159.
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(Human) Phosphohistidine phosphatase 1 belongs to the Janus family, and has 2 isoforms produced by alternative splicing, and 6 transcripts. It is encoded by the PHPT1 gene, located on the 9th chromosome.


Contents

Structure

Solution structure of a Human Phosphohistidine Phosphatase 1 monomer

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Generality

Phosphohistidine phosphatase 1 is a 14kDa homotrimeric protein, which monomers contain all 125 amino acids. Furthermore, one monomer contains 4 α helices, 6 β strands and 2 turns.

Domains

PHPT1 contains 2 acetylation site and a N-acetylalanine site There is also an Janus/Ocnus family region, characteristic.

It has one substrate binding site, and one proton acceptor active site.

Disease

Relevance

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

</StructureSection>

References

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